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Gerlach, Nadine

Archived Page

This web page has not been updated since the former colleague left MARUM.

 

CV

since 07/2017 Ph.D. stu­dent in the Joint Re­search Group for Mar­ine Gly­cobi­o­logy (MARUM Cen­ter for Mar­ine En­vir­on­mental Sci­ences at the Uni­versity Bre­men and Max Planck In­sti­tute for Mar­ine Mi­cro­bi­o­logy in Bremen)
07-08/2017                                                  

research cruise Polarstern PS107

https://doi.org/10.2312/BzPM_0717_2018
07/2018 - present

PhD representative MARUM/GLOMAR
10/2014 - 07/2017                                                      

Master of Science in Microbiology at the Carl von Ossietzky University, Oldenburg, Germany

Master thesis: Biochemical and structural analysis of marine polysaccharide lyases
10/2011 - 09/2014

Bachelor of Science in Biology at the University Bremen, Germany

Bachelor thesis: Potential of manganese reduction in marine subsurface sediments of Helgoland

 

PhD project: Molecular mechanism of enzymatic recycling of anionic glycans by marine microbes

An important step in the (marine) carbon cycle is the remineralisation of algal polysaccharides by heterotrophic bacteria. Marine algae consist of up to 70 % of polysaccharides, which physically support the thallus of macroalgae, have storage properties or are part of extracellular transparent exo-polymer particles (TEP). Polysaccharide-degrading bacteria specialize on glycans resulting in a pronounced niche partitioning with respect to algal polysaccharide degradation during and after algal blooms. Studying the degradation mechanisms of abundant key degraders will contribute to our knowledge on the ecophysiology of marine bacteria, and thus to our understanding of the biogeochemical cycles in the oceans.

In this PhD project, we investigate the utilization of the anionic polysaccharide fucoidan, the main cell wall component of brown seaweed. In more particular, we study the molecular mechanisms of putative CAZymes in order to gain insights into the remineralisation of fucoidan by heterotrophic bacteria.

 

Research interest

  • Marine microbiology
  • Marine ecology
  • Marine carbon cycle
  • Algal polysaccharides
  • Carbohydrate active enzymes (CAZymes)
  • Structural biology

 

Conference contributions and awards

15th Summer Course Glycosiences

(24-28th June 2018, Wageningen, The Neatherlands)

Poster presentation Enzymatic recycling of sulphated algal polysaccharides by marine microbes

winner of 3rd poster prize

attendance half-funded by GLOMAR Graduate School

MIMAS II

(20th-22nd August, 2018, Greifswald, Germany)

Poster presentation Enzymatic recycling of sulphated algal polysaccharides by marine microbes

YOUMARES 9

(11-14th September, 2018, Oldenburg, Germany)

Oral presentation Enzymatic recycling of sulphated algal polysaccharides by marine microbes

at­ten­dance half-fun­ded by GLO­MAR Gra­dua­te School

12th Bremen PhD Days

(17-18th April, 2019, Bremen, Germany)

Oral presentation Enzymatic recycling of anionic polysaccharides by marine microbes

attendance fun­ded by GLO­MAR Gra­dua­te School

ICYMARE 2019 BREMEN

(24-27th September, 2019, Bremen, Germany)

Poster presentation Enzymatic kit to detect and quantify the abundant algal polysacchairde alginate

Session host - organiszing the session on microbial ecology

 

 

Publications

  • The CAZypedia Consortium (2017). Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes. Glycobiology, Volume 28, Issue 1, January 2018, Pages 3–8. DOI.org/10.1093/glycob/cwx089

Chapter: Polysaccharide lyase family 7

Gerlach, N. & Hehemann, J.-H.

  • Reisky, L., Préchoux, A., Zühlke, M.-K., Bäumgen, M., Robb, C. S., Gerlach, N., Roret, T., Stanetty, C., Larocque, R., Michel, G., Song, T., Markert, S., Unfried, F., Mihovilovic, M. D., Trautwein-Schult, A., Becher, C., Schweder, T., Bornscheuer, U. T., Hehemann, J.-H. (2019). A marine bacterial cascade degrades the algal polysaccharide ulvan. Nature Chemical Biololgy. DOI : 10.1038/s41589-019-0311-9.
  • Schewe, I. (2018). The Expedition PS107 of the Research Vessel POLARSTERN to the Fram Strait and the AWI-HAUSGARTEN in 2017, Berichte zur Polar- und Meeresforschung = Reports on polar and marine research, Bremerhaven, Alfred Wegener Institute for Polar and Marine Research, 717 , 120 p. DOI.org/10.2312/BzPM_0717_2018

Chapter 8: FUNCTIONAL GLYCOMICS OF ALGAL BLOOMS IN THE ARCTIC OCEAN

Gerlach, N., Becker, S., Hehemann, J.-H.